- The words "enteric-coated" on the label.
- A reliable company. Consumer Lab did a comparison of common brands of SAM-e.
Most studies have used daily doses of no less than 800 mg per day. However, many practitioners recommend starting with 400 mg per day and then increasing the dose depending on the results.
SAM-e should be taken on an empty stomach. If nausea or heartburn occur, drinking more water may help. Many people notice that SAM-e can be stimulating, so it should be taken earlier in the day to avoid insomnia.
